A review on CRISPR-Cas system based applications in Oncology
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2022
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| Online toegang: | http://hdl.handle.net/10361/17517 |
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10361-175172022-10-18T21:01:36Z A review on CRISPR-Cas system based applications in Oncology Sadia, Mir Sayka Khan, Tanisha Tabassum Department of Pharmacy, Brac University CRISPR-Cas Cancer treatment Immunotherapy CRISPR applications Disease models Oncology Genetic engineering Gene editing--Technological innovations. CRISPR-associated protein 9. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 61-68). Cancer is one of the leading causes of death around the world. The ability to proliferate at a rapid rate, metastasize, and form heterogeneous tumors due to mutagenic occurrences renders cancer as one of the most difficult-to-treat diseases in the world. Owing to its high accuracy and efficiency, the gene editing tool Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and CRISPR-associated (Cas) enzymes have shown immense potential in the treatment of genome-based diseases, especially cancer. The ability to deliberately activate or repress genes, allows CRISPR-Cas systems to discover novel targets for new potential anti-cancer drugs. In this review, the mechanism of different classes of CRISPR-Cas systems are summarized. Several other applications including diagnostic and therapeutic applications of CRISPR-Cas systems in the field of oncology are also addressed in this review. Mir Sadia B. Pharmacy 2022-10-18T04:19:05Z 2022-10-18T04:19:05Z 2022 2022-02 Thesis ID: 18146057 http://hdl.handle.net/10361/17517 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 68 Pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
en_US |
| topic |
CRISPR-Cas Cancer treatment Immunotherapy CRISPR applications Disease models Oncology Genetic engineering Gene editing--Technological innovations. CRISPR-associated protein 9. |
| spellingShingle |
CRISPR-Cas Cancer treatment Immunotherapy CRISPR applications Disease models Oncology Genetic engineering Gene editing--Technological innovations. CRISPR-associated protein 9. Sadia, Mir A review on CRISPR-Cas system based applications in Oncology |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Sayka Khan, Tanisha Tabassum |
| author_facet |
Sayka Khan, Tanisha Tabassum Sadia, Mir |
| format |
Thesis |
| author |
Sadia, Mir |
| author_sort |
Sadia, Mir |
| title |
A review on CRISPR-Cas system based applications in Oncology |
| title_short |
A review on CRISPR-Cas system based applications in Oncology |
| title_full |
A review on CRISPR-Cas system based applications in Oncology |
| title_fullStr |
A review on CRISPR-Cas system based applications in Oncology |
| title_full_unstemmed |
A review on CRISPR-Cas system based applications in Oncology |
| title_sort |
review on crispr-cas system based applications in oncology |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17517 |
| work_keys_str_mv |
AT sadiamir areviewoncrisprcassystembasedapplicationsinoncology AT sadiamir reviewoncrisprcassystembasedapplicationsinoncology |
| _version_ |
1814309505522991104 |