The Pharmacological potential of lupeol and derivatives: A corroborative analysis

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.

Bibliographic Details
Main Author: Sowa, Rodoshi Mahfuz
Other Authors: Ashrafi, Sania
Format: Thesis
Language:English
Published: Brac University 2023
Subjects:
Online Access:http://hdl.handle.net/10361/18135
id 10361-18135
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spelling 10361-181352023-04-11T21:01:46Z The Pharmacological potential of lupeol and derivatives: A corroborative analysis Sowa, Rodoshi Mahfuz Ashrafi, Sania Department of Pharmacy, Brac University Phytochemical Lupeol Analogue Confined Carcinoma Triterpenoid Rodents Anti-Angiogentic Melanoma Clutter Expansion Lipidemia Cyclophosphamide Divergent Hepatoprotective Pharmaceutical technology. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 52-71). Recently researchers are centered on creating drug-like substance as an elective to the accessibledrugs with less adverseeffects.Besides, peopleproceed to be influenced by a fewillnessesbasically due to environmentalstrengths such as drug-fightingorganisms as well ascontaminations. Lupeol is a natural triterpenoid which along with its derivatives exists in a considerable quantity in eatablenatural products and vegetables, and medicinal plants. A plenty of studies about the biological activity of lupeol and its subsidiary derivatives have been conducted and it has been demonstrated that they have broad pharmacological possibilitiesinside them specifically or in a roundabout way. There are also some pharmacokinetic studies, which indicated its bioavailability, absorption, distribution, polarity, excretion rate, AUC and other pharmacokinetic parameters. Along with some structural modifications and derivatives, lupeol has shown significant potency in better pharmacokinetic and pharmacological action in many in-vivo as well as in-vitro studies. The goal of this survey paper is to collaborate all the major biological capacities of this novel compound and its subsidiary derivatives along with the mechanisms of action, clinical as well as preclinical study results, applications in treatment, some limitations and future prospects. Rodoshi Mahfuz Sowa B. Pharmacy 2023-04-11T04:07:50Z 2023-04-11T04:07:50Z 2022 2022-02 Thesis ID: 18146086 http://hdl.handle.net/10361/18135 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 71 pages application/pdf Brac University
institution Brac University
collection Institutional Repository
language English
topic Phytochemical
Lupeol
Analogue
Confined
Carcinoma
Triterpenoid
Rodents
Anti-Angiogentic
Melanoma
Clutter
Expansion
Lipidemia
Cyclophosphamide
Divergent
Hepatoprotective
Pharmaceutical technology.
spellingShingle Phytochemical
Lupeol
Analogue
Confined
Carcinoma
Triterpenoid
Rodents
Anti-Angiogentic
Melanoma
Clutter
Expansion
Lipidemia
Cyclophosphamide
Divergent
Hepatoprotective
Pharmaceutical technology.
Sowa, Rodoshi Mahfuz
The Pharmacological potential of lupeol and derivatives: A corroborative analysis
description This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
author2 Ashrafi, Sania
author_facet Ashrafi, Sania
Sowa, Rodoshi Mahfuz
format Thesis
author Sowa, Rodoshi Mahfuz
author_sort Sowa, Rodoshi Mahfuz
title The Pharmacological potential of lupeol and derivatives: A corroborative analysis
title_short The Pharmacological potential of lupeol and derivatives: A corroborative analysis
title_full The Pharmacological potential of lupeol and derivatives: A corroborative analysis
title_fullStr The Pharmacological potential of lupeol and derivatives: A corroborative analysis
title_full_unstemmed The Pharmacological potential of lupeol and derivatives: A corroborative analysis
title_sort pharmacological potential of lupeol and derivatives: a corroborative analysis
publisher Brac University
publishDate 2023
url http://hdl.handle.net/10361/18135
work_keys_str_mv AT sowarodoshimahfuz thepharmacologicalpotentialoflupeolandderivativesacorroborativeanalysis
AT sowarodoshimahfuz pharmacologicalpotentialoflupeolandderivativesacorroborativeanalysis
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