Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023.
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Brac University
2024
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| Länkar: | http://hdl.handle.net/10361/23619 |
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10361-236192024-06-27T21:01:42Z Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review Akter, Honufa Sharmin, Sabrina School of Pharmacy, Brac University Doxorubicin Breast cancer Liposome Liposomal doxorubicin Cardiotoxicity Metastasis Breast cancer--Treatment. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. Cataloged from the PDF version of the thesis. Includes bibliographical references (pages 35-48). Breast cancer continues to be one of the most common reasons for hospitalization and mortality each year. As time goes on, novel anticancer drug formulations are being released on the market, raising the concern of medical professionals due to their superiority, toxicology, and cost-effectiveness compared to the traditional formulation of the same drugs. Doxorubicin is an effective cancer drug that comes in three forms: pegylated liposomal, nonpegylated liposomal, and conventional non-liposomal. Although it is more expensive, liposomal doxorubicin has been shown to have a more favorable toxicological profile than conventional. The cost-effectiveness of liposomal doxorubicin has not been thoroughly investigated due to the small number of research that have been conducted. Apart from that this article highlights the use of traditional doxorubicin has been somewhat restricted due to the adverse effects it can produce, whereas liposomal formulation has favorable safety profile. In the overall treatment of breast cancer, the formation of a liposomal form of doxorubicin, which is less harmful to the heart, better tolerated, and just as effective, expands the therapeutic alternatives available. Honufa Akter B. Pharmacy 2024-06-27T05:39:19Z 2024-06-27T05:39:19Z 2023 2023-07 Thesis ID 19346039 http://hdl.handle.net/10361/23619 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Doxorubicin Breast cancer Liposome Liposomal doxorubicin Cardiotoxicity Metastasis Breast cancer--Treatment. |
| spellingShingle |
Doxorubicin Breast cancer Liposome Liposomal doxorubicin Cardiotoxicity Metastasis Breast cancer--Treatment. Akter, Honufa Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2023. |
| author2 |
Sharmin, Sabrina |
| author_facet |
Sharmin, Sabrina Akter, Honufa |
| format |
Thesis |
| author |
Akter, Honufa |
| author_sort |
Akter, Honufa |
| title |
Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| title_short |
Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| title_full |
Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| title_fullStr |
Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| title_full_unstemmed |
Comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| title_sort |
comparison of conventional doxorubicin with liposome encapsulated doxorubicin as a treatment of breast cancer-a review |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/23619 |
| work_keys_str_mv |
AT akterhonufa comparisonofconventionaldoxorubicinwithliposomeencapsulateddoxorubicinasatreatmentofbreastcancerareview |
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1814307750369296384 |