A review on the teratogenic effects of isotretinoin
This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024.
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Brac University
2024
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| Online Access: | http://hdl.handle.net/10361/24292 |
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10361-242922024-10-03T06:46:51Z A review on the teratogenic effects of isotretinoin Anisha, Tahsina Binte Kashem Islam, Farzana School of Pharmacy, Brac University Retinoic acid Isotretinoin Teratogenic effects Prenatal exposure Teratogenesis. Reproductive toxicology. Pharmacology--Side effects. This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. Cataloged from PDF version of project report. Includes bibliographical references (pages 43-45). This review article presents recent studies on isotretinoin, a potent oral retinoid that is frequently recommended to treat severe acne but has been clearly associated with teratogenic effects when given to expectant mothers. The motive of this review article is to provide an in-depth overview of the teratogenic effects of isotretinoin and the necessity of strict safety measures to protect fetuses. Isotretinoin is known to be teratogenic; prenatal exposure has been linked to a variety of congenital defects, with the central nervous system, cardiovascular system, and face structures being the most commonly affected. In this review comparative studies of pregnant women with teratogenic effect have been analyzed with numerical data from FAERS database about different teratogenic effect found in fetus and other adverse events. The aim of this review is to analyze the FAERS public database to identify the outcomes reported when pregnant women are exposed to isotretinoin. The review article concludes with proposals for more future study directions as well as a discussion of the research's implications for effective policy reforms. Tahsina Binte Kashem Anisha B. Pharmacy 2024-10-02T08:53:42Z 2024-10-02T08:53:42Z ©2024 2024-01 Project report ID 19346014 http://hdl.handle.net/10361/24292 en Brac University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 46 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Retinoic acid Isotretinoin Teratogenic effects Prenatal exposure Teratogenesis. Reproductive toxicology. Pharmacology--Side effects. |
| spellingShingle |
Retinoic acid Isotretinoin Teratogenic effects Prenatal exposure Teratogenesis. Reproductive toxicology. Pharmacology--Side effects. Anisha, Tahsina Binte Kashem A review on the teratogenic effects of isotretinoin |
| description |
This project report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2024. |
| author2 |
Islam, Farzana |
| author_facet |
Islam, Farzana Anisha, Tahsina Binte Kashem |
| format |
Project report |
| author |
Anisha, Tahsina Binte Kashem |
| author_sort |
Anisha, Tahsina Binte Kashem |
| title |
A review on the teratogenic effects of isotretinoin |
| title_short |
A review on the teratogenic effects of isotretinoin |
| title_full |
A review on the teratogenic effects of isotretinoin |
| title_fullStr |
A review on the teratogenic effects of isotretinoin |
| title_full_unstemmed |
A review on the teratogenic effects of isotretinoin |
| title_sort |
review on the teratogenic effects of isotretinoin |
| publisher |
Brac University |
| publishDate |
2024 |
| url |
http://hdl.handle.net/10361/24292 |
| work_keys_str_mv |
AT anishatahsinabintekashem areviewontheteratogeniceffectsofisotretinoin AT anishatahsinabintekashem reviewontheteratogeniceffectsofisotretinoin |
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