Concepts and models for drug permeability studies : cell and tissue based In vitro culture models - Sarmento, Bruno (Amsterdam : Elsevier, 2016)
3.3.4.1.2 Alternatives to the Caco-2 model3.3.4.2 Caco-2/HT29-MTX model; 3.3.4.3 Caco-2/Raji B model; 3.3.4.4 Caco-2/HT29-MTX/Raji B; 3.3.4.5 Novel 3D in vitro models; 3.3.5 Validation studies; 3.3.6 Conclusions; References; 3.4 -- Cell-based in vitro models for nasal permeability studies; 3.4.1 Introduction; 3.4.2 Nasal primary cell culture models; 3.4.2.1 Sampling approaches and procedures; 3.4.2.2 HNE cell preparation and culture initiation; 3.4.3 Immortalized nasal cell lines; 3.4.3.1 RMPI 2650 cell line; 3.4.3.2 BT cell line; 3.4.3.3 Human lung carcinoma cell line
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Includes bibliographical references and index.
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Keywords: Cell culture; Drugs -- Physiological transport -- Research -- Methodology; Drugs -- Testing; Epithelial cells; Cell culture; Drugs -- Testing; Epithelial cells; MEDICAL / Pharmacology; Permeability; Pharmacokinetics; Cell Culture Techniques; Models, Biological; Pharmaceutical Preparations -- metabolism; Tissue Culture Techniques; Electronic books; Electronic books